Evan Patel

BS Chemistry, Yale University, 2015

As an undergraduate, I primarily conducted research in organic chemistry with a focus on the synthesis of clinically relevant molecules. While in the lab of Dr. Jonathan Ellman I worked on more efficient synthesis of trisubstituted nitroalkenes using urea organocatalysts. I also spent a summer in the lab of Dr. Stephen Hashmi where I characterized the efficiency and enantioselectivity of gold-catalyzed allene cyclizations. As a medical student at Northwestern University Feinberg School of Medicine, I realized that I want to emphasize laboratory/translational research on biomolecular mechanisms as part of my career in academic medicine. I became an HHMI Medical Fellow in the Littman lab where I hope to further elucidate the effects of gut microbiota on distal tumors and immune checkpoint blockade with the anticipation that a more fundamental knowledge of this process will improve the scope of antitumor immunotherapies.



1. Phelan, J., Patel, E., Ellman, J. Catalytic Enantioselective Addition of Thioacids to Trisubstituted Nitroalkenes. Angew. Chem. Int. Ed. 2014; 53: 11329-11332.